eBay U.S. has an option to delete unused profiles.
Go to My eBay → My Account → Business Policies.
There is a button labeled ‘Clean Up Policies’ and it should delete all policies not used in any of your current listings. With any luck it should leave you with the 5 or so that you currently are using.
Policies (Profiles) are useful for reasons explained above and are easy to use, edit, and create on eBay and are easily recognized in your GS listings.
I have also setup a ‘managed payment’ profile which stops the ‘PayPal’ warning messages when listing.
Hope this helps.